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In vitro cell assays show greater binding of glioblastoma-derived U251 exosomes compared with normal NHA exosomes (images taken at 200× magnification). (a) NHA cells+ U251 exosomes, (b) NHA cells+ NHA exosomes, (c) U251 cells+ U251 exosomes and (d) U251 cells+ NHA exosomes. Cell nuclei are stained with 4′,6-diamidino-2-phenylindole (blue) and exosomes are stained with 1,1′-dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate (red).
