Table 1.

Primary indications for regular aspirin use among randomly selected subsets of self-reported aspirin users in the HPFS and NHS cohorts.

Cohort	HPFSa	NHSb
N surveyed	Quantity not specified	1–6 tablets/week	7+ tablets/week
	211	100	100
Aspirin use indication (%)c
Cardiovascular disease
Treatment/management	25	NR	NR
Prevention	58	9	8
Musculoskeletal paind	33	30	50
Headache	25	32	18
Headache and musculoskeletal pain	NR	16	15
Other	7	13	9

^aThe HPFS survey was conducted among randomly selected men who reported regular use of aspirin on surveys from 1986–1990 and was first reported in: Giovannucci E, Rimm EB, Stampfer MJ, Colditz GA, Ascherio A, Willett WC. Aspirin use and the risk for colorectal cancer and adenoma in male health professionals. Ann Intern Med 1994;121(4):241–246 [reference 27].

^bThe NHS survey was conducted among randomly selected women who reported the indicated level of regular aspirin use on surveys from 1980–1984 and was first reported in: Manson JE, Stampfer MJ, Colditz GA, Willett WC, Rosner B, Speizer FE, et al. A prospective study of aspirin use and primary prevention of cardiovascular disease in women. JAMA 1991;266(4):521–527 [reference 30].

^cMen were allowed to report more than one indication; women selected only one.

^dThe musculoskeletal pain category included arthritis on the NHS survey.

Abbreviations: HPFS, Health Professionals Follow-up Study; NHS, Nurses’ Health Study; NR, not reported