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. Author manuscript; available in PMC: 2014 Jan 23.
Published in final edited form as: Future Virol. 2013 Dec 1;8(12):1151–1160. doi: 10.2217/fvl.13.107

Figure 1.

Figure 1

Schematic overview and time course of vaccine study. GPCMV seronegative outbred Hartley guinea pigs were immunized twice (interval of 3 weeks between doses), with vAM409 vaccine, or placebo. Small-volume bleeds were performed by toenail clip were obtained (arrowheads) on all guinea pigs following vaccination at weeks 2, 3, 5, 7, 9 and 11, for both quantitative PCR analysis of viral load and for analysis of antibody response. Challenge with SG-passaged GPCMV was administered on days 89–91 of the experiment, approximately 7–8 weeks after initiation of breeding.