Figure 3.

(a) A synXPC micro-CT coronal image of the same naive mouse tibial epiphysis shown in figure 1a but after applying an artificial lesion (white arrow) on the surface of the articular cartilage using a surgical scalpel; (b) histomorphometry validation of the synXPC image, showing the small lesion (black arrow) on the articular cartilage of the mouse tibial epiphysis (haematoxylin and eosin/safranin staining of decalcified paraffin sections); (c) close-up view of the portion of the cartilage with the lesion. (Online version in colour.)