Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Biotransformation of benzo[a]pyrene.
PAHs are metabolized in first phase of xenobiotic biotransformation to form several phenols (hydroxy derivatives), phenol diols, dihydrodiols, quinones, and reactive diol-epoxide’s enantiomers. The reactive species are then conjugated to GSH-conjugates glucuronides and sulphate esters to enable better excretion and detoxification of metabolized xenobiotics owing to increased hydrophilicity.
