TABLE 2.
Gene | Polymorphism | The main observations related to polymorphism (association) |
---|---|---|
CYP1A1 | m1 = 3801 T>C | Lung cancer, CAD |
m2 = 2455 A>G; Ile>Val | Lung cancer, breast cancer | |
m4 = 2453 C>A; Thr>Asp | Lung cancer | |
| ||
GSTM1 | deletion | Oxidative stress, decreased enzyme activities, cancer, CAD |
GSTT1 | deletion |
CYP - cytochrome P450; GSTM1 - glutathione S-transferase M1; GTST1 - glutation S-transferase T1