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. 2013 Oct 15;23(3):255–265. doi: 10.11613/BM.2013.032

TABLE 2.

The most common CYP1A1, GSTM, and GSTT polymorphisms.

Gene Polymorphism The main observations related to polymorphism (association)
CYP1A1 m1 = 3801 T>C Lung cancer, CAD
m2 = 2455 A>G; Ile>Val Lung cancer, breast cancer
m4 = 2453 C>A; Thr>Asp Lung cancer

GSTM1 deletion Oxidative stress, decreased enzyme activities, cancer, CAD
GSTT1 deletion

CYP - cytochrome P450; GSTM1 - glutathione S-transferase M1; GTST1 - glutation S-transferase T1