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. 2013 Oct 9;23(4):1002–1012. doi: 10.1093/hmg/ddt496

Figure 8.

Figure 8.

cGMP levels are reduced in retina lacking Aipl1. (A) cGMP levels in P15 retina obtained from animals adapted to dark (D) or light (L) conditions. Each value shown is the mean of cGMP levels (pmol/mg protein) obtained from three independent samples. *P < 0.005, Nrl−/−Aipl1+/− versus Nrl−/− Aipl1−/− double knockout mice by Student's t-test. The small reduction in cGMP levels between dark and light conditions in Nrl−/− Aipl1−/− was statistically not significant. (B) Dissected dorsal (D) and ventral (V) regions of retina from Nrl−/− Aipl1−/− and littermate control Nrl−/− Aipl1+/− at P12 were used to measure cGMP levels by an enzyme immunoassay kit. Each value shown is the mean of cGMP levels obtained from three independent samples. *P < 0.01, Nrl−/− Aipl1+/− versus Nrl−/− Aipl1−/− double knockout mice by Student's t-test.