Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Oct 15;23(4):1045–1055. doi: 10.1093/hmg/ddt500

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author 2013. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com

PMC Copyright notice

Figure 3. — Differentially expressed genes between monoallelic and biallelic RTT-iPSCs. (A and B) Venn diagram represents the number of (A) highly or (B) lowly expressed genes in RTT-wt-iPSCs and RTT-mu-iPSCs compared with RTT-bi-iPSCs (P < 0.05). Thus, the common genes in (A) were defined as monoallelic iPSC-specific and in (B) as biallelic iPSC-specific genes. (C) Comparison of the ratio of differentially expressed X-linked genes between short (<60 600 kbp) and long arms (>60 600 kbp). (D and E) (D) The percentage of differentially expressed genes in each chromosome between RTT-wt-iPSCs and RTT-bi-iPSCs and (E) between RTT-mu-iPSCs and RTT-bi-iPSCs. The ratio was calculated by dividing the absolute amount of differentially expressed genes by the total number of genes per chromosome. (F and G) Chromosomal distribution of differentially-expressed genes in (F) chromosome X and (G) chromosome 8. Black and gray bars represent average of log2(FPKM) value in RTT-wt-iPSCs and RTT-bi-iPSCs, respectively. Error bar represents standard deviation of log2(FPKM).