Table 2:

Ontology classes, descriptions, BFO and IDO class types and source ontology

Class	Description	BFO class type	IDO class type	Source ontology
Bacteria	Bacteria are a large group of single-celled prokaryotic organisms, which may have a variety of shapes ranging from spherical, rod-like, comma-shaped to spiral.	Independent Continuant: object	Bacteria	Bacteria is a term in the IDO core imported from NCBITaxon.
Infectious disease	A disease whose physical basis is an infectious disorder.	Dependent Continuant: realizable entity	Disease	“Infectious disease” is a term in the IDO core and is a subtype of “disease” which is imported to IDO core from Ontology for General Medical Science.
Antibiotic	A chemotherapeutic agent or substance that kills (microbicidal) or inhibits (microbiostatic) the growth of bacteria and treats bacterial infections.	Independent Continuant: object	Antibiotic	“Antibiotic” is a term in IDO core which is linked to the term “antibiotic” in ChEBI.
Bacterial quality	The properties of bacteria that allow bacteria to be classified according to phenotypic or morphologic features. These properties assist with narrowing the differential diagnosis before definitive culture results are available.	Dependent Continuant: quality	Quality	“Bacterial quality” is a subtype of “quality” imported to IDO core from BFO.