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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: J Immunol. 2013 Dec 27;192(3):919–928. doi: 10.4049/jimmunol.1301979

Figure 6. Specific deletion of Lyn in B cells leads to myeloproliferative phenotype comparable to lyn−/−.

Figure 6

(A-C) Absolute numbers of total myeloid cells (A), monocytes/macrophages (B) and granulocytes (C) in the spleens of 8 month-old control, lyn−/− and B-lyn−/− mice.

(D) Weights of spleens harvested from control, lyn−/− and B-lyn−/− mice were recorded at 2, 4, 6 and 8 months of age.

(E) Absolute numbers of conventional DCs in the spleens of 8 month-old control, lyn−/− and B-lyn−/− mice.

(F) MFI (relative to control) of CD86 expressed by conventional DCs in the spleens of 8 month-old mice. Bars represent mean ± SEM of independent experiments from 6-10 mice per group.

(G) Absolute numbers of plasmacytoid DCs in the spleens of 8 month-old control, lyn−/− and B-lyn−/− mice.

(H) MFI (relative to control) of MHCII expressed by plasmacytoid DCs in the spleens of 8 month-old mice. Bars represent mean ± SEM of independent experiments from 6-10 mice per group.

(A-E, G) Data represent mean of independent experiments. Each dot represents an individual mouse. (A-H) * P ≤ 0.05, ** P ≤ 0.01 (One-way ANOVA).