. Author manuscript; available in PMC: 2015 Feb 1.

Published in final edited form as: J Immunol. 2013 Dec 27;192(3):919–928. doi: 10.4049/jimmunol.1301979

Table I.

Histological scoring^a

	Nephritis	C3	IgG
Control	0.00 ± 0.00	0.00 ± 0.00	0.0 ± 0.0
*lyn^−/−*	1.40 ± 0.20 ** vs. control	1.40 ± 0.89 ^* vs. control	1.40 ± 0.40
B-lyn^−/−	1.50 ± 0.19 *** vs. control	0.63 ± 0.26	1.12 ± 0.35
*B-lyn^−/− myd88^−/−*	0.40 ± 0.24 ^* vs. lyn^−/− ** vs. B-lyn^−/−	0.17 ± 0.17 ^* vs. lyn^−/−	0.33 ± 0.21

Kidney inflammation was scored in a blinded fashion as described in Materials and Methods. Briefly, the presence and severities of the disease in the glomerular and interstitial compartments were arbitrarily graded as 0 (absent), 1 (mild), 2 (moderate) or 3 (severe). Data are averaged from at least 5 microscopic fields per specimen, with 5-7 mice (8 month-old) per group.

P ≤ 0.05 versus control (One-way ANOVA).