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. Author manuscript; available in PMC: 2014 Dec 5.
Published in final edited form as: Cell Stem Cell. 2013 Dec 5;13(6):720–733. doi: 10.1016/j.stem.2013.10.003

Fig. 2. Inducible β-catenin deletion or Dkk1 expression in anagen inhibits hair follicle matrix proliferation without loss of stem cells.

Fig. 2

Krt5-rtTA tetO-Cre Ctnnb1fl/flmutants, Dkk1 transgenics and Dkk1/Krm1 transgenics, and their respective littermate controls mice were induced from P4 (A–T) or P7 (U–Y’) and skin samples harvested at the stages indicated. (A–J) Ki67 immunofluorescence (A,B, red; C–J, green). (K–O) TUNEL staining (green) (yellow arrows). (P–Y) KRT15 immunofluorescence (P,Q, red; RY, green) (white arrows). Insets in (P–T) represent higher magnification photographs of regions indicated by arrows. (U’–Y’) CD34 immunofluorescence (U’,V’, red; W’–Y’, green) (white arrows). Scale bars: 50 µm (A–E, K–O, U–Y’); 100 µm (F–J, P–T). See also Fig. S2.