Table 2.
In-hospital outcome measures, stratified by treatment assignment
| Variable | Twice Daily (n = 21) | Continuous (n = 20) | p Value |
|---|---|---|---|
| Furosemide dose (mg/24 h) | 162 ± 48 160 (140 to 200) |
162 ± 52 160 (120 to 240) |
1.00 |
| Δ creatinine (mg/dl) | −0.02 ± 0.39 0.1 (−0.1 to 0.2) |
0.13 ± 0.34 0.05 (−0.05 to 0.35) |
0.18 |
| Urine output (ml) | 5,113 ± 2,258 4,675 (3,230 to 6,250) |
4,894 ± 2,205 4,448 (3,625 to 4,650) |
0.64 |
| Δ weight (kg) | −1.64 ± 2.34 −2.55 (−3.30 to 0.25) |
−2.66 ± 2.44 −2.10 (−4.85 to ± 1.25) |
0.27 |
| Δ serum potassium (mEq/L) | −0.07 ± 0.57 −0.2 (−0.5 to 0.3) |
0.22 ± 0.67 0.3 (−0.2 to 0.7) |
0.08 |
| Rates of hypokalemia (<3.5 mEq/L) | 5 (24%) | 2 (10%) | 0.44 |
| Δ serum sodium (mEq/L) | −2.19 ± 3.25 −2 (−5 to 0) |
−1.15 ± 3.12 −1 (−4 to 1) |
0.30 |
| Δ systolic blood pressure (mm Hg) | −5.6 ± 21.2 −3 (−15 to 7) |
2.9 ± 15.0 0 (−2 to 4) |
0.11 |
| Length of stay (days) | 8.86 ± 3.82 7 (5.5 to 11) |
9.85 ± 11.72 7 (4.5 to 9.5) |
0.69 |
Data are expressed as mean ± SD and as median (interquartile range). Measured from admission (hospital day 0) until hospital day 3 or discharge (whichever came first), except for length of stay.