Table 3. Effect of pressure on thermodynamic parameters of spin transitions in CYP261D1.
| P450 species |
Pressure, bar |
ΔH, kcal/mol | ΔS, cal/mol·grad | ΔV, ml/mola |
|---|---|---|---|---|
| 261D1(−) | 1 500 |
32.5 ±3.9 22.7 ±6.3 |
118.8 ±12.5 62.2 ±6.9 |
−46.8 |
| 261D1(+) | 1 500 |
21.7 ±1.4 25.5 ±8.8 |
81.7 ±5.5 89.0 ±33.1 |
+18.3 |
*
The values given in the table represent the averages of 2-4 individual measurements, and the “±” values show the confidence interval calculated for p = 0.05.
a
Apparent value of molar volume change in low-to-high spin transition calculated according to equation (2).