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. Author manuscript; available in PMC: 2015 Jan 25.
Published in final edited form as: Mol Cell Endocrinol. 2013 Oct 5;382(1):218–226. doi: 10.1016/j.mce.2013.09.023

Fig. 1. Oxidative stress response proteins help maintain protein structure and function.

Fig. 1

SOD1 dismutates superoxide to form H2O2 and other cellular enzymes including catalase (Cat) and Trx, which activates peroxiredoxins (Prx), help eliminate H2O2. Cat and Prx convert H2O2 to H2O and O2. Together, Trx, Ape1, and PDI reduce cellular proteins to maintain their native protein structure and function. Adapted from Ref.(Webster et al 2001).