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. Author manuscript; available in PMC: 2015 Jan 25.
Published in final edited form as: Mol Cell Endocrinol. 2013 Oct 5;382(1):218–226. doi: 10.1016/j.mce.2013.09.023

Fig. 3. E2 treatment differentially regulates Trx, SOD1, Ape1, and PDI mRNA levels.

Fig. 3

RNA was isolated from the uteri of ovariectomized female mice that had been treated with oil or E2. cDNA was synthesized and (A) Trx, (B) SOD1, (C) Ape1, and (D) PDI mRNA levels were determined using quantitative real time PCR. Each sample was normalized to the amount of hypoxanthine phosphorybosyl transferase (HPRT) mRNA present. E2 induced significant differences in the mRNA expression of Trx (*, p<0.05), SOD1 (**, p<0.01), and Ape1 (**, p<0.01), but not PDI (p=0.63). Seven mice were included in the oil- and E2-treated groups as indicated at the base of each treatment group bar.