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. 2014 Jan 23;10(1):e1004118. doi: 10.1371/journal.pgen.1004118

Figure 4. Disruption of FGFR1-Frs2/3 pathway decreases the number of vestibular hair cells.

Figure 4

(A, B) No change in HC number was detected between E16.5 Six1enh21-Cre::Fgfr1flox/+ (A) and Six1enh21-Cre::Fgfr1flox/flox utricles (B) labeled with anti-Myo7a antibody. (C, D) Fewer HCs were observed in the utricle of E16.5 Fgfr1 ΔFrs/ΔFrs mutants (D) than Fgfr1 ΔFrs/+ control (C). Ampullary HCs are also included (asterisks). Scale bar: A–D; 200 µm (in D).