Table 3. Treatment efficacy studies on soil-transmitted helminth infections conducted in Honduras from May 1930 to June 30, 2012 (n = 17).
| Drug | Dose | Year | Population | Ascaris | Trichuris | Hookworms | Ref. | |||
| n | CR (%) | n | CR (%) | n | CR (%) | |||||
| Albendazole | 400 mg (single dose) | 1986 | General | 82 | 80.5 | 75 | 66.7 | 16 | 100.0 | [96] |
| 1989 | Children | 40 | 90.0 | 40 | 92.6 | 40 | 100.0 | [97] | ||
| 1990 | Children | — | — | — | — | 20 | 80.0 | [48] | ||
| Mebendazole | 100 mg BID/3 days | 1983 | Children | 21 | 90.5 | 18 | 94.4 | 4 | 100.0 | [98] |
| 1986 | General | 83 | 78.3 | 75 | 65.3 | 11 | 100.0 | [96] | ||
| 1987 | Children | 45 | 97.8 | — | — | — | — | [99] | ||
| 1987 | Children | 81 | 44.4 | 58 | 70.7 | 21 | 9.5 | [100] | ||
| 1989 | Children | 37 | 86.5 | 37 | 67.9 | 37 | 88.9 | [97] | ||
| 1989 | Children | — | — | 7 | 100.0 | 4 | 100.0 | [101] | ||
| 1990 | Children | — | — | — | — | 20 | 90.0 | [48] | ||
| Piperazine citrate | 75 mg/kg BID/2 days | 1987 | Children | 24 | 62.5 | — | — | — | — | [99] |
| 1989 | Children | 37 | 73.0 | 37 | 68.8 | 37 | 20.0 | [97] | ||
| 75 mg/kg BID/3 days | 1983 | Children | 21 | 90.5 | 20 | 0.0 | 1 | 0.0 | [98] | |
| 75 mg/kg BID/7 days | 1989 | Children | 23 | 87.0 | — | — | — | — | [101] | |
| 1989 | Children | 88 | 62.5 | — | — | — | — | [102] | ||
| 100 mg/kg (single dose) | 1987 | Children | 24 | 58.3 | — | — | — | — | [99] | |
| 1989 | Children | 88 | 42.0 | — | — | — | — | [102] | ||
| 1 g BID/6 days | 1955 | Adults | 34 | 97.0 | 22 | 0.0 | 15 | 26.4 | [47] | |
| 2 g (single dose)/6 days | 1955 | Adults | 51 | 92.1 | 52 | 5.7 | 33 | 15.1 | [47] | |
| 3 g (single dose)/2 days | 1956 | Children | 30 | 96.6 | — | — | — | — | [103] | |
| Thiabendazole | 50 mg/kg BID/3 days | 1969 | Children | — | — | 76 | 85.5 | 17 | 52.9 | [104] |
| 1969 | Children | 43 | 27.5 | 10 | 80 | [105] | ||||
| Levamisole | 3 mg/kg (single dose) | 1970 | Children | 42 | 97.6 | 18 | 44.4 | 10 | 80.0 | [106] |
| Pyrantel | 10 mg/kg (single dose) | 1975 | Children | 13 | 92.0 | 33 | 8.0 | — | — | [107] |
| 1983 | Children | 21 | 100.0 | 19 | 0.0 | 2 | 100.0 | [98] | ||
| 20 mg/kg/3 days | 1975 | Children | — | — | — | — | 15 | 100.0 | [107] | |
| Pyrantel-Oxantel | 100 mg (single dose) | 1987 | Children | 81 | 25.9 | 60 | 80.0 | 20 | 10.0 | [99] |
| Dithiazanine iodide | 20 mg/kg/5 days | 1960 | Children | 41 | 95.0 | 38 | 98.0 | 10 | 89.0 | [108] |
| 600 mg/5 days | 1967 | General | — | — | 51 | 72.5 | — | — | [109] | |
| Diethylcarbamazine | 25 mg/kg/4 days | 1954 | General | 30 | 80.0 | — | — | — | — | [110] |
| Sodium santoninate | 250 mg/6 days | 1954 | General | 38 | 35.3 | — | — | — | — | [110] |
| Hexylresorcinol | 1 g (single dose) | 1954 | General | 80 | 42.0 | — | — | — | — | [110] |
| Chenopodium-chloroform | 15 mL in castor oil | 1954 | General | 80 | 40.0 | — | — | — | — | [110] |