Table 2. Characteristics of patients.
Patients with ATLI | Patients with elevated | Patients with normal | |
ALT,AST, or bilrubin | ALT, AST, bilirubin | ||
Mean age in years (range) | 37 (24–56) | 43 (26–60) | 46 (27–61) |
BMI (kg/m2) | 20.3 (18.4–22.6) | 21.0(19.3–22.7) | 21.4 (19.5–22.9) |
INH (mg/kg/day) | 4.8 (4.6–5.4) | 5.2 (4.7–5.8) | 5.4 (4.7–6.0) |
PZA (mg/kg/day) | 16.1 (15.2–17.9) | 17.2 (15.6–19.2) | 17.9 (15.6–20.0) |
Liver function tests at 2 months: | |||
ALT | 110.0 (84.3–147.0) | 45.6 (37.5–54.8) | 22.2 (16.8–29.0) |
AST | 91.4 (66.2–114.0) | 42.5 (35.3–51.0) | 23.0 (17.0–30.0) |
bilirubin (µmol/L) | 9.7 (5.1–16.5) | 11.0 (6.7–14.0) | 9.7 (6.0–12.5) |