Table 2. Minor allele frequencies in HBV carriers, resolved HBV and uninfected subjects in Thailand.
| HBV carriers vs. Resolved | HBV carriers vs. Uninfected | ||||||||
| SNPs | Gene | Minor allelesa | HBV carriersb (2n = 898) | Resolved (2n = 226) | Uninfected (2n = 246) | OR (95% CI) | P values | OR (95% CI) | P values |
| rs3077 | HLA-DPA1 | T | 227 (25.3%) | 84 (37.2%) | 86 (35.0%) | 0.57 (0.42–0.78) | <0.001 | 0.63 (0.47–0.85) | 0.008 |
| rs9277378 | HLA-DPB1 | A | 237 (26.4%) | 85 (37.6%) | 96 (39.0%) | 0.59 (0.44–0.81) | 0.001 | 0.56 (0.42–0.75) | <0.001 |
| rs3128917 | HLA-DPB1 | G | 459 (51.1%) | 108 (47.8%) | 122 (49.6%) | 1.14 (0.85–1.53) | 0.372 | 1.06 (0.80–1.41) | 0.673 |
| rs1419881 | TCF19 | C | 361 (40.2%) | 103 (45.6%) | 126 (51.2%) | 0.80 (0.60–1.08) | 0.142 | 0.64 (0.48–0.85) | 0.002 |
| rs652888 | EHMT2 | C | 329 (36.6%) | 76 (33.6%) | 84 (34.1%) | 1.14 (0.84–1.55) | 0.400 | 1.11 (0.83–1.50) | 0.478 |
Abbreviation: CI, confidence interval; OR, odds ratio.
a
Defined by using data from public database (NCBI).
b
Defined as the combination between HCC and CHB.