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. 2014 Jan 23;9(1):e86034. doi: 10.1371/journal.pone.0086034

Figure 8. Effect of transduced PEP-1-PON1 protein on TPA-induced ear edema.

Figure 8

Ears of mice were treated with TPA (1 µg/ear) and PEP-1-PON1 protein and controls (PON1 protein and PEP-1 peptide) was topically applied to mice ears 1 h after TPA treatment. The inhibition of TPA-induced ear edema was analyzed by hematoxylin and eosin immunostaining (A) and measuring changes in ear thickness (B) as well as weight of 5 mm ear biopsy (C). Scale bar = 50 µm for A (top panel), except for 25 µm in high magnifications in A (bottom panel). **P<0.01, compared with TPA treated mice.