Table 1. DNA vaccine regimens in rhesus macaques.
| Macaque | DNA Delivery | Priming Vaccine (number of vaccinations) | Heterologous DNA Boost |
| L862 | IM/EP | p24CE1+p24CE2 (2×) | COT-M p55gag |
| M166 | IM/EP | p24CE1+p24CE2 (2×) | COT-M p55gag |
| M695 | IM/EP | p24CE1+p24CE2 (2×) | COT-M p55gag |
| R279 | IM/EP | p24CE1+p24CE2 (2×) | COT-M p55gag |
| R315a | IM/EP | p24CE1+p24CE2 (2×) | COT-M p55gag |
| P302a | IM/EP | p24CE1+p24CE2 (2×) | COT-M p55gag |
| P307a | IM/EP | p24CE1+p24CE2 (2×) | COT-M p55gag |
| P308a | IM/EP | p24CE1+p24CE2 (2×) | COT-M p55gag |
| P314b , c | IM/EP | p24CE1+p24CE2 (3×) | COT-M p55gag |
| M437b , c | IM/EP | p24CE1+p24CE2 (3×) | COT-M p55gag |
| L863 | IM/EP | p24CE1+p24CE2+COT-M p55gag (3×) | none |
| M629 | IM/EP | p24CE1+p24CE2+COT-M p55gag (3×) | none |
| P572 | IM/EP | p24CE1+p24CE2+COT-M p55gag (3×) | none |
| R285 | IM/EP | p24CE1+p24CE2+COT-M p55gag (3×) | none |
| L985 | IM/EP | COT-M p55gag (2×) | p24CE1+p24CE2 |
| P574 | IM/EP | COT-M p55gag (2×) | p24CE1+p24CE2 |
| R067 | IM/EP | COT-M p55gag (2×) | p24CE1+p24CE2 |
| R288 | IM/EP | COT-M p55gag (2×) | p24CE1+p24CE2 |
| M085c | IM/EP | HXB2 p37gag (6×) | none |
| M114c | IM/EP | HXB2 p37gag (6×) | none |
| M121c | IM/EP | HXB2 p37gag (6×) | none |
| 3169c | IM | HXB2 p55gag (5×) | none |
| 3274c | IM | HXB2 p55gag (5×) | none |
| 3278c | IM | HXB2 p55gag (5×) | none |
| 3290c | IM | HXB2 p55gag (5×) | none |
a
Vaccine consists of a dual expression plasmid producing the p24CE1+p24CE2 antigens.
b
Received prior 3 vaccinations with the DNAs expressing the poorly immunogenic unmodified p24CE.
c
Vaccine did not include IL-12 DNA adjuvant.