Table 3. Higher response rate and broader responses among the 7 CE in the p24CE DNA vaccinated macaques.
| Vaccine (Number of animals) | Cellular immune responses to individual CEa | Positive CE/animal | Response Rate | ||||||||
| ID | CE1 | CE2 | CE3 | CE4 | CE5 | CE6 | CE7 | # | Range | ||
| p24CE DNA (10) | L862 | + | + | + | 3 | 1–3 | 100% | ||||
| M166 | + | + | + | 3 | |||||||
| M695 | + | + | + | 3 | |||||||
| R279 | + | + | + | 3 | |||||||
| P314 | + | + | + | 3 | |||||||
| M437 | + | 1 | |||||||||
| R315 | + | + | 2 | ||||||||
| P302 | + | + | + | 3 | |||||||
| P307 | + | + | + | 3 | |||||||
| P308 | + | + | 2 | ||||||||
| WT gag DNA (11) | L985 | + | + | 2 | 0–2 | 45% | |||||
| P574 | + | 1 | |||||||||
| R067 | + | + | 2 | ||||||||
| R288 | + | 1 | |||||||||
| M121 | + | + | 2 | ||||||||
| 3169 | 0 | ||||||||||
| 3274 | 0 | ||||||||||
| 3278 | 0 | ||||||||||
| 3290 | 0 | ||||||||||
| M085 | 0 | ||||||||||
| M114 | 0 | ||||||||||
| p24CE+p55gag (4) | L863 | + | + | + | 3 | 0–3 | 75% | ||||
| M629 | + | + | 2 | ||||||||
| P572 | 0 | ||||||||||
| R285 | + | + | + | 3 | |||||||
a
CE responses were evaluated 2 weeks after the priming vaccination shown in Table 1 using a peptide pool spanning the 7 individual CE (combination of 15-mer overlapping by 11AA and 10-mer overlapping by 9AA).