Table 1. Socio-demographic and clinical characteristics of the individuals in the three experimental groups.
| Healthy ControlsN = 20 | PDaMCI N = 16 | aMCINPD N = 20 | Fisher F (df = 2,53) | P value | |
| Male/female | 11/9 | 10/6 | 11/9 | ||
| Mean (SD) | |||||
| Age | 67.5 (6.0) | 66.1 (8.1) | 69.7 (6.6) | 1.28 | >0.20 |
| Education (years) | 12.8 (4.2) | 11.7 (4.6) | 10.9 (4.9) | 0.86 | >0.40 |
| MMSE | 29.1 (1.2)* | 27.3 (1.9) | 25.9 (2.6) | 17.4 | <0.001 |
| CDR | 0.5 | 0.5 | |||
| UPDRS | 25.5 (11.5) | ||||
| Hoehn & Yahr scale | 2.3 (0.7); = 1 - two subjects; = 2 -six subjects; = 2.5 - one subject; = 3 - seven subjects | ||||
| Duration of Disease | 4.9 (3.8) | ||||
| Apathy evaluation scale | Range: 21–36; Mean = 30.1; SD = 4.5 | ||||
| Beck Depression Inventory | Range: 3–14; Mean = 8.0; SD = 3.6 | ||||
| ADL | Range: 4–6 | All subjects = 6 | |||
| IADL | Range: 5–8 | All subjects = 8 | |||
| Pill Questionnaire | >2 | ||||
*
Indicates a significant difference from both aMCIPD and aMCINPD subjects (p<0.01 in both cases) resulting from application of Tukey’s HSD test for unequal samples.
UPDRS: Unified Parkinson’s disease Rating Scale-Part III [34].
PDaMCI: PD patients with amnestic mild cognitive impairment (isolated or associated with other cognitive changes).
aMCINPD: individuals with amnestic mild cognitive impairment (isolated or associated with other cognitive changes) without PD.