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pH of drinking water affects the T1D incidence in NOD mice. Female NOD mice from in-house SPF colony (2nd- or 3rd-generation NOD/ShiLtJ mice) and 3- to 4- and 8-week-old mice purchased from JAX were maintained on either AW or NW and monitored for hyperglycemia (n = 10/group) as described for Fig. 1. While half the JAX mice were switched to NW or continued on AW upon arrival, in-house mice were on AW or NW starting at gestation stage.
