Skip to main content
. 2014 Jan 23;9(1):e86569. doi: 10.1371/journal.pone.0086569

Table 1. Comparison in gene expression level between normal and tumor tissues.

Gene symbol Gene title Fold changea Adjuste P-valueb
ANO1 anoctamin 1, calcium activated chloride channel 0.48 6.1×10−5
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.56 1.8×10−9
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 0.54 3.3×10−6
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 0.27 7.2×10−7
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 1.48 2.8×10−5
CLCC1 chloride channel CLIC-like 1 1.52 1.6×10−8
CLCN3 chloride channel, voltage-sensitive 3 1.39 5.7×10−4
CLCN7 chloride channel, voltage-sensitive 7 1.80 2.1×10−12
CLIC3 chloride intracellular channel 3 0.17 6.6×10−13
CLIC4 chloride intracellular channel 4 0.62 8.1×10−7
CLIC5 chloride intracellular channel 5 0.06 3.3×10−20
CLIC6 chloride intracellular channel 6 3.28 3.7×10−8
KCNAB1 potassium voltage-gated channel, shaker-related subfamily, beta member 1 0.26 2.1×10−12
KCNAB2 potassium voltage-gated channel, shaker-related subfamily, beta member 2 0.62 1.2×10−5
KCNJ2 potassium inwardly-rectifying channel, subfamily J, member 2 0.50 4.8×10−5
KCNJ8 potassium inwardly-rectifying channel, subfamily J, member 8 0.25 2.8×10−15
KCNK1 potassium channel, subfamily K, member 1 2.32 5.1×10−6
KCNK3 potassium channel, subfamily K, member 3 0.09 3.2×10−20
KCNK5 potassium channel, subfamily K, member 5 4.77 1.5×10−12
KCNMB4 potassium large conductance calcium-activated channel, subfamily M, beta member 4 0.24 4.3×10−8
KCNQ3 potassium voltage-gated channel, KQT-like subfamily, member 3 2.69 1.4×10−8
KCNT2 potassium channel, subfamily T, member 2 0.10 2.4×10−18
MCOLN1 mucolipin 1 0.72 6.2×10−5
MCOLN2 mucolipin 2 0.54 1.9×10−5
MCOLN3 mucolipin 3 0.29 6.4×10−9
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.69 1.6×10−7
PKD2 polycystic kidney disease 2 (autosomal dominant) 0.64 1.7×10−5
SCN4B sodium channel, voltage-gated, type IV, beta subunit 0.13 1.5×10−14
SCN7A sodium channel, voltage-gated, type VII, alpha subunit 0.16 4.2×10−10
SCNN1B sodium channel, non-voltage-gated 1, beta subunit 0.36 1.3×10−6
SCNN1G sodium channel, non-voltage-gated 1, gamma subunit 0.20 6.0×10−10
TPCN1 two pore segment channel 1 0.76 7.8×10−4
TRPC1 transient receptor potential cation channel, subfamily C, member 1 0.49 5.3×10−8
TRPC6 transient receptor potential cation channel, subfamily C, member 6 0.31 4.6×10−9
TRPM2 transient receptor potential cation channel, subfamily M, member 2 1.53 1.2×10−5
TRPV2 transient receptor potential cation channel, subfamily V, member 2 0.34 1.2×10−13
VDAC1 voltage-dependent anion channel 1 1.36 6.1×10−5
a

Fold change is calculated by dividing the expression of tumor tissue by the expression of normal tissue.

b

P-value is calculated by paired t-test and adjusted by Benjamini & Hochberg correction.