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. Author manuscript; available in PMC: 2015 Mar 15.
Published in final edited form as: Methods. 2013 Jul 23;66(2):168–179. doi: 10.1016/j.ymeth.2013.07.026

Figure 4.

Figure 4

Figure 4

FRET transition density plots for HMM assigned FRET states in Pgp. (A–D) 4-state HMM results for the four biochemical conditions (A) 'verapamil transport', (B) 'apo', (C) 'vanadate-inhibited', (D) 'cyclosporin transport'. Upper row, FRET transitions between sequential FRET states Si and Si+1; lower row, FRET transitions between next but one FRET states Si and Si+2. (E–H) 9-state HMM results for the four biochemical conditions (E) 'verapamil transport', (F) 'apo', (G) 'vanadate-inhibited', (H) 'cyclosporin transport'. Upper row, FRET transitions between sequential FRET states Si and Si+1; lower row, FRET transitions between next but one FRET states Si and Si+2. Color map coding indicates minimal and maximal occurrences of FRET transitions for each plot.