An official website of the United States government
Here's how you know
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Modified intent-to-treat analysis for the ad hoc subgroup analysis of participants with severe pain and insomnia symptoms at baseline. Multiple imputation was used (10 imputations) to accommodate missing data at baseline and 18-mo follow-up