Table 1. Comparison of study participants with and without data on glycoprotein receptor density, n = 127.
Variable | All patients; n = 127 | Patients stratified for glycoprotein receptor analysis | |||
With analysis; n = 59 (46.5%) | Without analysis; n = 68 (53.5%) | p | |||
Basic patients' characteristics | Age in years, mean (sd) | 53.3 (17.1) | 59.5 (13.6) | 48.0 (18.1) | < 0.001 |
Female gender, n (%) | 62 (48.8) | 27 (45.8) | 35 (51.5) | 0.521 | |
Smoker, n (%)& | 68 (54.8) | 32 (56.1) | 36 (53.7) | 0.788 | |
Tinnitus, n (%)&& | 91 (75.2) | 39 (72.2) | 52 (77.6) | 0.495 | |
Vertigo, n (%)&& | 46 (37.7) | 18 (32.7) | 28 (41.8) | 0.304 | |
Laboratory values | GPIa-gene | ||||
CC (wild type), n (%) | 28 (22.1) | 9 (15.3) | 19 (27.9) | 0.085 | |
TC or TT, n (%) | 99 (77.9) | 50 (84.7) | 49 (72.1) | ||
BcLI-gene | |||||
CC (wild type), n (%) | 82 (64.6) | 40 (67.8) | 42 (61.8) | 0.478 | |
TC or TT, n (%) | 45 (35.4) | 19 (32.2) | 26 (38.2) | ||
A312-gene | |||||
CC, n (%) | 77 (60.6) | 33 (55.9) | 44 (64.7) | 0.313 | |
TC or TT, n (%) | 50 (39.4) | 26 (44.1) | 24 (35.3) | ||
HaeIII-gene | |||||
CC (wild type), n (%) | 78 (61.4) | 37 (62.7) | 41 (60.3) | 0.780 | |
TC or TT, n (%) | 49 (58.6) | 22 (37.3) | 27 (39.7) | ||
Fibrinogen in mg/dl, mean (sd) | 280.1 (78.9) | 277.5 (72.7) | 282 (84.5) | 0.729 | |
Hearing recovery | None, n (%) | 43 (33.9) | 18 (30.5) | 25 (36.8) | |
1-10 dB, n (%) | 46 (36.2) | 19 (32.2) | 27 (39.7) | 0.160§ | |
> 10 dB, n (%) | 38 (29.9) | 22 (37.3) | 16 (23.5) |
& = data missing on 3 patients; && = data missing on 6 patients; CC = wild type, TC = heterozygous; TT = homozygous; § = Mantel-Haenszel Chi-square test.