Table 3. Results of binary logistic regression analyses, dependent variable = hearing improvement >10 dB, independent variables = GPIa receptor density and fibrinogen, n = 49#.
GPIa receptor density above mean | GPIa receptor density below mean | ORs (95%-CI) for GPIa receptor density within different strata of fibrinogen | |||
N with/without hearing improvement | OR (95% CI) | N with/without hearing improvement | OR (95% CI) | ||
Fibrinogen above mean | 1/9 | 1.0 | 5/10 | 1.24 (0.59 – 2.60); p = 0.568 | 1.24 (0.59 – 2.60); p = 0.568 |
Fibrinogen below mean | 8/13 | 1.50 (0.71 – 3.14); p = 0.286 | 5/17 | 0.84 (0.29 – 2.42); p = 0.741 | 0.56 (0.25 – 1.24); p = 0.150 |
Measure of effect modification on additive scale: relative excess risk due to interaction, RERI (95% CI) = −0.90 (−1.97 – 0.17)
Measure of effect modification on multiplicative scale: ratio of ORs (95% CI) = 0.45 (0.21 – 0.94), p = 0.034
ORs are adjusted for smoking and vertigo, # = 4 datasets missing due to missing covariates.