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. 2014 Jan 23;9(1):e86988. doi: 10.1371/journal.pone.0086988

Figure 5. Levels of phosphorylated STEP61 and CREB in mice with intrastriatal inhibition of PKA.

Figure 5

(A) Levels of phosphorylated STEP61 at Ser221 and (B) phosphorylated CREB at Ser133 were evaluated in the dorsal striatum of trained mice injected with vehicle (saline) or Rp-cAMPS at the second day of training. Data represent the mean of relative optical density of phosphorylated STEP61 and phosphorylated CREB (expressed as a percentage of control values) ± S.E.M. Values are respectively expressed relative to total STEP and total CREB. Values are from triplicate experiments/animal, n = 4 mice/group. ***p<0.001 vs. vehicle-treated mice.