Table 2. Passive transfer of EAE.
Donor | Recipient | Number of animals | Incidence (%) | Day of onset | Maximum disease severity |
WT | WT | 5 | 3/5 (60) | 14±0a) | 1.3±0.3a) |
WT | Was−/− | 5 | 0/5 (0) | - | 0 |
Was−/− | WT | 4 | 0/4 (0) | - | 0 |
EAE was induced with injection of 5×106 T-cell blasts per mouse derived from WT or Was−/− mice actively immunized with MOG35–55 peptide. a)Data represent mean ± SEM for those mice that developed the disease.