Table 1.
Characteristics of HCC patients analyzed in this study
| Serial no. | Gender | Age (y) | Cause of liver disease* | Focality† | Size‡ | AFP (ng/mL)§ | Grading|| | Bmf¶ |
|---|---|---|---|---|---|---|---|---|
| 1 | M | 65 | HBV + ethanol | Uni | 3 | 5 | G2 | X |
| 2 | M | 52 | None | Uni | 5 | 5 | G2 | |
| 3 | M | 70 | HCV | Uni | 4 | 35 | G3 | X |
| 4 | F | 65 | HCV | Uni | 3 | 3 | G3 | X |
| 5 | F | 62 | HCV | Uni | 3 | 76 | G3 | X |
| 6 | M | 67 | HCV | Uni | 6 | 3,352 | G3 | |
| 7 | M | 77 | HBV-Ab | Uni | 5 | 4 | G3 | X |
| 8 | M | 70 | Ethanol | Uni | 5 | 537 | G3 | X |
| 9 | M | 65 | HCV + ethanol | Uni | 3 | 20 | G3 | X |
| 10 | F | 80 | HCV | Uni | 5 | 76 | G3 | X |
| 11 | F | 59 | HCV | Uni | 6 | 7 | G4 | |
| 12 | F | 66 | HCV | Uni | 8 | 9,572 | G3 | |
| 13 | F | 68 | None | Uni | 5.5 | 2 | G3 | X |
| 14 | M | 59 | HCV | Uni | 5 | 86 | G3 | X |
| 15 | F | 82 | HCV | Uni | 7.5 | 964 | G3 | X |
| 16 | M | 60 | Ethanol | Uni | 2 | 156 | G2 | |
| 17 | M | 78 | HCV | Uni | 3 | 9 | G2 | X |
| 18 | M | 54 | HBV | Uni | 4 | 162 | G2 | X |
| 19 | M | 69 | HCV | Uni | 10 | 390 | G3 | |
| 20 | M | 74 | None | Uni | 11 | 78 | G3 | X |
| 21 | M | 73 | HCV | Uni | 4.5 | 2 | G3 | X |
| 22 | M | 77 | HCV | Uni | 2.2 | 48 | G2 | |
| 23 | F | 71 | HCV | Uni | 2 | 276 | G3 | X |
| 24 | M | 68 | HCV | Multi | 2.5 | 5 | G2 | X |
| 25 | M | 81 | HCV | Multi | 3 | 8 | G3 | |
| 26 | M | 74 | HCV | Multi | 3.5 | 2,198 | G3 | X |
| 27 | M | 74 | HCV + HBV | Multi | 3 | 75 | G4 | X |
| 28 | M | 82 | None | Multi | 5 | 4 | G3 | |
| 29 | M | 51 | HBV + HCV | Multi | 7 | 1,924 | G3 | X |
| 30 | M | 79 | HCV | Multi | 10 | 7 | G3 | X |
| 31 | M | 70 | HCV | Multi | 2.3 | 46 | G3 | |
| 32 | M | 72 | HCV | Multi | 3.4 | 18 | G3 | |
| 33 | M | 70 | None | Multi | 10 | 11 | G2 | |
| 34 | M | 75 | HCV | Multi | 7 | 9 | G3 | |
| 35 | M | 59 | HCV | Multi | 3 | 76 | G3 | X |
| 36 | M | 67 | None | Multi | 6 | 18,766 | G3 | |
| 37 | M | 65 | HCV | Multi | 6.5 | 167 | G3 | X |
| 38 | M | 76 | HBV-Ab | Multi | 5 | 10,000 | G4 | |
| 39 | M | 49 | HBV | Multi | 4 | 2,708 | G4 | |
| 40 | F | 53 | HCV | Multi | 4 | 60 | G3 | |
| 41 | F | 62 | HCV | Multi | 3 | 468 | G2 | |
| 42 | M | 79 | HBV | Multi | 7 | 540 | G4 | |
| 43 | M | 68 | HCV | Multi | 8 | 86 | G3 | |
| 44 | M | 65 | HCV | Multi | 7 | 139,313 | G4 | |
| 45 | M | 64 | HCV + ethanol | Multi | 6.5 | 8 | G3 | |
| 46 | M | 60 | HCV | Multi | 3.2 | 15 | G2 | |
| 47 | M | 60 | HCV | Multi | 1.3 | 257 | G4 | X |
| 48 | M | 58 | HCV | Multi | 3 | 132 | G3 | |
| 49 | M | 66 | HCV | Multi | 3 | 58 | G2 | X |
| 50 | M | 75 | HCV | Multi | 3 | 63 | G3 | X |
| 51 | M | 68 | HCV | Multi | 6.5 | 131 | G3 | X |
*
Cause of underlying liver disease: HBV, hepatitis B virus; HCV, hepatitis C virus; ethanol, history of ethanol abuse; HBV-Ab, presence of the antibodies against HBV; none, negative history for hepatitis virus infection and ethanol abuse.
†
Focality: Unifocality (Uni) or Multifocality (Multi) was assessed based on imaging techniques previous to surgery and by means of intraoperative ultrasound.
‡
Size of the HCC nodule (in cm) used for RNA and protein extraction.
§
AFP: α-fetoprotein determination was made before surgery.
||
Grading of the HCC was assessed according to Edmondson and Steiner’s criteria.
¶
X: Cases analyzed for Bmf expression.