Table 3.

Pearson correlation between CTQ, HAM-D₂₁, BMI, cortisol awakening response (measured as AUC) after placebo, dexamethasone and fludrocortisone in a linear regression model in depressive patients with early life stress (ELS) and without ELS.

Mean (SEM)	CTQ	AUC placebo	AUC dexamethasone	AUC fludrocortisone	HAMD	BMI
WITH ELS
CTQ	1	0.13	−0.34	−0.15	0.43	−0.84**
AUC placebo	0.13	1	0.11	0.51*	0.41	−0.03
AUC dexamethasone	−0.34	0.11	1	0.76**	−0.31	0.20
AUC fludrocortisone	−0.15	0.51*	0.76**	1	−0.05	0.18
HAMD	0.43	0.41	−0.31	−0.05	1	−0.40
BMI	−0.84**	−0.03	0.20	0.18	−0.40	1
WITHOUT ELS
CTQ	1	−0.34	−0.78*	−0.72*	−0.36	0.21
AUC placebo	−0.34	1	0.53*	0.69*	−0.35	0.19
AUC dexamethasone	−0.78*	0.53*	1	0.70*	−0.26	0.08
AUC fludrocortisone	−0.72*	0.69*	0.70*	1	0.15	−0.22
HAMD	−0.36	−0.35	−0.26	0.15	1	−0.49
BMI	0.21	0.19	0.08	−0.22	−0.49	1

ELS, early life stress; AUC, area under the curve from salivary cortisol immediately upon awakening, 30 and 60 min later (nmol × h/L); CTQ: Childhood Trauma Questionnaire; HAM-D₂₁, Hamilton Depression Rating Scale. R, Pearson correlation. BMI, body mass index. *p ≤ 0.05; **p ≤ 0.01.