Table 4. Hazard ratios of stroke incidence with metabolic components with or without central obesity (using various cut-off value of waist circumference) by sex.
| No. of supplementary components |
WC ≥80 cm | WC ≥85 cm | WC ≥90 cm | ||||||||||||
| No. of strokes/total |
Model 1a | Model 2b | No. of strokes/total | Model 1a | Model 2b | No. of strokes/total | Model 1a | Model 2b | |||||||
| HR | (95% CI) | HR | (95% CI) | HR | (95% CI) | HR | (95% CI) | HR | (95% CI) | HR | (95% CI) | ||||
| Males | |||||||||||||||
| Central obesity (−) | |||||||||||||||
| 0 | 5/208 | 1.00 | Reference | 1.00 | Reference | 8/259 | 1.00 | Reference | 1.00 | Reference | 8/280 | 1.00 | Reference | 1.00 | Reference |
| 1 | 17/215 | 2.58 | (0.94–7.04) | 2.52 | (0.92–6.91) | 20/298 | 1.81 | (0.79–4.14) | 1.73 | (0.75–3.97) | 23/374 | 1.83 | (0.81–4.10) | 1.75 | (0.78–3.95) |
| ≥2 | 9/80 | 3.76 | (1.26–11.27) | 3.24 | (1.05–9.98) | 13/128 | 2.93 | (1.21–7.08) | 2.53 | (1.02–6.24) | 17/169 | 2.99 | (1.28–6.95) | 2.50 | (1.05–5.95) |
| Central obesity (+) | |||||||||||||||
| 0 | 3/87 | 1.88 | (0.45–7.88) | 2.08 | (0.49–8.73) | 0/36 | — | — | — | — | 0/15 | — | — | — | — |
| 1 | 7/199 | 1.65 | (0.52–5.20) | 1.41 | (0.43–4.63) | 4/116 | 1.24 | (0.37–4.12) | 0.91 | (0.24–3.24) | 1/40 | 0.98 | (0.12–7.85) | — | — |
| ≥2 | 13/131 | 4.17 | (1.48–11.70) | 3.83 | (1.34–10.92) | 9/83 | 3.20 | (1.23–8.31) | 2.83 | (1.05–7.59) | 5/42 | 4.10 | (1.34–12.53) | 4.05 | (1.32–12.44) |
| Females | |||||||||||||||
| Central obesity (−) | |||||||||||||||
| 0 | 8/437 | 1.00 | Reference | 1.00 | Reference | 8/481 | 1.00 | Reference | 1.00 | Reference | 8/510 | 1.00 | Reference | 1.00 | Reference |
| 1 | 16/388 | 1.32 | (0.56–3.09) | 1.27 | (0.54–3.00) | 17/455 | 1.31 | (0.56–3.05) | 1.26 | (0.54–2.94) | 19/503 | 1.35 | (0.59–3.10) | 1.31 | (0.57–3.01) |
| ≥2 | 8/127 | 1.83 | (0.69–4.89) | 1.96 | (0.73–5.27) | 9/171 | 1.76 | (0.68–4.58) | 1.84 | (0.71–4.79) | 10/200 | 1.75 | (0.69–4.44) | 1.83 | (0.72–4.64) |
| Central obesity (+) | |||||||||||||||
| 0 | 0/87 | — | — | — | — | 0/43 | — | — | — | — | 0/14 | — | — | — | — |
| 1 | 3/151 | 0.52 | (0.14–1.96) | 0.53 | (0.14–2.12) | 2/82 | 0.62 | (0.13–2.95) | 0.70 | (0.15–3.34) | 0/36 | — | — | — | — |
| ≥2 | 7/95 | 2.30 | (0.88–6.38) | 2.42 | (0.87–6.72) | 6/51 | 3.83 | (1.33–11.07) | 4.38 | (1.51–12.75) | 5/22 | 8.64 | (2.82–26.51) | 9.09 | (2.95–28.03) |
HR: hazard ratio.
CI: confidence interval.
WC: Waist circumference.
aHazard ratios adjusted for age.
bHazard ratio adjusted for age, smoking status, and alcohol drinking status.