Table 4. Associations between individual HLA-A alleles and risk of cervical cancer, by smoking status.
| Never smoker | ||||||
| HLA-A | Cases (n = 88) |
Controls (n = 69) |
Age-adjusted odds ratios (95% CI) |
P value | Multivariate Odds ratios (95% CI)a |
P value |
| A*0101 | 3 | 1 | 0.42 (0.04–4.10) | 0.453 | 0.49 (0.05–4.94) | 0.542 |
| A*0201 | 20 | 16 | 1.06 (0.50–2.25) | 0.885 | 1.31 (0.58–2.94) | 0.511 |
| A*0206 | 23 | 9 | 0.43 (0.18–1.00) | 0.049 | 0.37 (0.15–0.90) | 0.028 |
| A*0207 | 6 | 5 | 1.02 (0.30–3.53) | 0.969 | 1.24 (0.34–4.46) | 0.745 |
| A*0218 | 1 | 0 | — | — | — | — |
| A*0301 | 0 | 1 | — | — | — | — |
| A*1101 | 14 | 18 | 2.01 (0.90–4.47) | 0.086 | 1.95 (0.85–4.48) | 0.116 |
| A*1102 | 0 | 0 | — | — | — | — |
| A*2402 | 53 | 46 | 1.28 (0.66–2.49) | 0.461 | 1.19 (0.59–2.39) | 0.631 |
| A*2407 | 0 | 0 | — | — | — | — |
| A*2420 | 3 | 1 | 0.42 (0.04–4.12) | 0.453 | 0.37 (0.04–3.76) | 0.399 |
| A*2601 | 10 | 6 | 0.77 (0.26–2.25) | 0.633 | 0.62 (0.19–2.00) | 0.424 |
| A*2602 | 5 | 2 | 0.46 (0.08–2.45) | 0.360 | 0.43 (0.07–2.46) | 0.343 |
| A*2603 | 1 | 3 | 4.48 (0.45–44.90) | 0.202 | 4.41 (0.41–48.03) | 0.223 |
| A*2606 | 0 | 0 | — | — | — | — |
| A*3101 | 11 | 13 | 1.64 (0.68–3.95) | 0.267 | 1.65 (0.68–4.04) | 0.270 |
| A*3303 | 16 | 9 | 0.65 (0.26–1.58) | 0.340 | 0.65 (0.26–1.62) | 0.357 |
| A*7401 | 0 | 0 | — | — | — | — |
| Ever smoker | ||||||
| HLA-A | Cases (n = 31) |
Controls (n = 50) |
Age-adjusted odds ratios (95% CI) |
P value | Multivariate odds ratios (95% CI)a |
P value |
| A*0101 | 1 | 1 | 0.60 (0.04–10.02) | 0.724 | 0.32 (0.01–7.46) | 0.480 |
| A*0201 | 5 | 8 | 1.02 (0.30–3.47) | 0.981 | 0.77 (0.20–2.93) | 0.673 |
| A*0206 | 9 | 6 | 0.33 (0.11–1.06) | 0.063 | 0.23 (0.06–0.89) | 0.033 |
| A*0207 | 2 | 6 | 2.10 (0.39–11.38) | 0.388 | 2.66 (0.44–16.25) | 0.289 |
| A*0218 | 0 | 0 | — | — | — | — |
| A*0301 | 0 | 0 | — | — | — | — |
| A*1101 | 2 | 3 | 0.89 (0.14–5.71) | 0.900 | 0.78 (0.11–5.50) | 0.801 |
| A*1102 | 0 | 1 | — | — | — | — |
| A*2402 | 12 | 31 | 2.63 (1.04–6.63) | 0.041 | 3.43 (1.26–9.36) | 0.016 |
| A*2407 | 0 | 1 | — | — | — | — |
| A*2420 | 0 | 1 | — | — | — | — |
| A*2601 | 5 | 6 | 0.70 (0.19–2.52) | 0.580 | 0.86 (0.23–3.32) | 0.832 |
| A*2602 | 3 | 2 | 0.39 (0.06–2.48) | 0.318 | 0.22 (0.03–1.72) | 0.232 |
| A*2603 | 3 | 0 | — | — | — | — |
| A*2606 | 1 | 0 | — | — | — | — |
| A*3101 | 7 | 13 | 1.20 (0.42–3.45) | 0.730 | 1.04 (0.34–3.21) | 0.946 |
| A*3303 | 7 | 8 | 0.62 (0.20–1.96) | 0.417 | 0.75 (0.22–2.61) | 0.652 |
| A*7401 | 0 | 1 | — | — | — | — |
aMultivariate models adjusted for age, drinking, gravidity, oral contraceptive use, and menopausal status.