Table 5. HRs^a and 95% CIs^a of all-cause mortality in 21 038 men by BMI^a category, stratified by age group.

	BMI
	<18.5	18.5–20.9	21.0–22.9	23.0–24.9	25.0–27.4	27.5–29.9	≥30.0
Total
No.	732	3677	5617	5657	3726	1213	416
Person-years	6282	35 339	55 681	57 157	37 954	12 484	4162
No. of deaths	270	805	1004	861	513	165	67
Mortality rateb	43.0	22.8	18.0	15.1	13.5	13.2	16.1
Age-smoking-adjusted HRs	2.78 (2.42–3.18)	1.49 (1.35–1.64)	1.19 (1.09–1.22)	1.00 (reference)	0.90 (0.81–1.00)	0.90 (0.76–1.06)	1.11 (0.87–1.43)
Multivariate HRs1c	1.42 (1.23–1.65)	1.10 (0.99–1.22)	1.04 (0.95–1.14)	1.00 (reference)	1.01 (0.90–1.13)	1.10 (0.92–1.31)	1.44 (1.11–1.87)
Multivariate HRs2d	1.52 (1.31–1.76)	1.14 (1.03–1.26)	1.06 (0.96–1.16)	1.00 (reference)	1.00 (0.89–1.12)	1.06 (0.89–1.26)	1.39 (1.07–1.81)
Multivariate HRs3e	1.35 (1.15–1.59)	1.06 (0.95–1.19)	1.01 (0.92–1.12)	1.00 (reference)	0.99 (0.88–1.12)	1.05 (0.87–1.26)	1.42 (1.07–1.88)
40–64 y
No.	310	2159	3591	3852	2637	903	312
Person-years	3053	21 992	36 885	40 026	27 421	9425	3221
No. of deaths	47	224	340	305	211	75	33
Mortality rateb	15.4	10.2	9.2	7.6	7.7	8.0	10.2
Age-smoking-adjusted HRs	1.76 (1.29–2.39)	1.25 (1.05–1.49)	1.17 (1.01–1.37)	1.00 (reference)	1.07 (0.90–1.28)	1.17 (0.91–1.51)	1.54 (1.08–2.21)
Multivariate HRs1c	1.26 (0.92–1.73)	1.07 (0.89–1.28)	1.11 (0.95–1.30)	1.00 (reference)	1.14 (0.95–1.37)	1.27 (0.97–1.66)	1.71 (1.17–2.50)
Multivariate HRs2d	1.32 (0.96–1.82)	1.09 (0.91–1.31)	1.12 (0.96–1.32)	1.00 (reference)	1.12 (0.93–1.35)	1.22 (0.93–1.60)	1.64 (1.12–2.40)
Multivariate HRs3e	1.24 (0.87–1.78)	1.11 (0.92–1.35)	1.13 (0.95–1.34)	1.00 (reference)	1.16 (0.96–1.41)	1.20 (0.90–1.61)	1.62 (1.07–2.45)
65–79 y
No.	422	1518	2026	1805	1089	310	104
Person-years	3229	13 347	18 796	17 131	10 533	3059	941
No. of deaths	223	581	664	556	302	90	34
Mortality rateb	69.1	43.5	35.3	32.5	28.7	29.4	36.1
Age-smoking-adjusted HRs	1.88 (1.61–2.20)	1.26 (1.12–1.41)	1.06 (0.94–1.18)	1.00 (reference)	0.91 (0.79–1.05)	0.96 (0.77–1.19)	1.21 (0.86–1.71)
Multivariate HRs1c	1.49 (1.26–1.76)	1.11 (0.98–1.26)	1.01 (0.90–1.14)	1.00 (reference)	0.94 (0.81–1.09)	1.01 (0.80–1.27)	1.25 (0.87–1.80)
Multivariate HRs2d	1.59 (1.35–1.89)	1.16 (1.03–1.32)	1.03 (0.92–1.16)	1.00 (reference)	0.93 (0.80–1.07)	0.97 (0.77–1.23)	1.23 (0.86–1.76)
Multivariate HRs3e	1.48 (1.23–1.78)	1.09 (0.96–1.25)	0.98 (0.87–1.11)	1.00 (reference)	0.88 (0.76–1.03)	0.91 (0.71–1.17)	1.22 (0.83–1.79)

^aHR, hazard ratio; CI, confidence interval; BMI, body mass index.

^bMortality rate was defined as number of deaths per 1000 person-years.

^cMultivariate HRs1 were adjusted for age in 5-year categories; weight change since age 20 years (loss of 10.0 kg or more, loss of 5.0–9.9 kg, change of less than ±5.0 kg, gain of 5.0–9.9 kg, or gain of 10.0 kg or more); education (junior high school or less, high school, or college/university or higher); marital status (married or unmarried); cigarette smoking (never smoker, past smoker, current smoker consuming 1–19 cigarettes per day, or current smoker consuming at least 20 cigarettes per day); alcohol drinking (never drinker, past drinker, or current drinker); time spent walking per day (less than 1 hour, or 1 hour or longer); sports and physical exercise time per week (less than 1 hour, 1–2 hours, 3–4 hours, or 5 hours or longer); history of kidney disease (yes or no); history of liver disease (yes or no).

^dMultivariate HRs2 were further adjusted for history of hypertension (yes or no) and history of diabetes (yes or no).

^eMultivariate HRs3 excluded from multivariate HRs2 the 473 men who died within the 2 years after baseline.