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. 2014 Jan 24;8:7. doi: 10.3389/fncel.2014.00007

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Copyright © 2014 Mòdol, Mancuso, Alé, Francos-Quijorna and Navarro.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Serotonin (5-HT) projections to MN pools in the lumbar spinal cord of 16 weeks old SOD1^G93A mice and wild type littermates. (A) Respresentative confocal images show increased 5-HT projections in SOD1^G93A compared to wild type mice. Scale bar 20 μm. (B) Quantification of the immunolabeling shows a 2 fold increase of 5-HT labeled area in SOD1^G93A animals at 16 weeks of age. Values are mean ± s.e.m. ^*p < 0.05 vs. wild type.