Brown adipose tissue metabolism and cold exposure tolerance.
A, H&E staining on BAT isolated from 12-week-old male wild type and aP2-G0S2 mice (10×). B, transmission electron microscopy on BAT isolated from 12-week-old male wild type and aP2-G0S2 mice (Scale bar, top = 10 μm; bottom = 500 nm). C, 12-week-old mice were fasted and placed in a 4 °C environment. Body temperature was measured as indicated over 6 h (n = 8 per group). ***, p < 0.0001.