TABLE 1.

Gene expression in BAT and WAT from aP2-G0S2 mice

qPCR results are from aP2-G0S2 mice and represented as relative expression compared with wild type. All tissues were normalized to β-actin expression as described under “Experimental Procedures” (n = 7 per gene/per group).

Gene ID	Gene function	Fed	6-h fast
White adipose tissue
IL-6	Proinflammatory	1.016 ± 0.36	1.024 ± 0.50
TNF-α	Proinflammatory	1.003 ± 0.76	1.029 ± 0.26
CCL2	Proinflammatory	1.028 ± 0.42	1.034 ± 0.81
CCL3	Proinflammatory	0.980 ± 0.71	0.961 ± 0.30
CCL7	Proinflammatory	1.043 ± 0.15	1.016 ± 0.37
CXCL1	Proinflammatory	1.033 ± 0.38	1.072 ± 0.39
Socs3	Proinflammatory	1.008 ± 0.28	1.005 ± 0.31
Socs5	Proinflammatory	0.994 ± 0.08	0.996 ± 0.20
CD68	Macrophage marker	1.017 ± 0.09	1.051 ± 0.31
CD116	Macrophage marker	1.017 ± 0.32	0.991 ± 0.36
CoxIV	Metabolic/oxidative	1.046 ± 0.28	1.009 ± 0.28
PGC-1α	Metabolic/oxidative	0.940 ± 0.24	0.982 ± 0.31
CPT1β	Metabolic/oxidative	0.982 ± 0.34	0.933 ± 0.12
PPAR-α	Metabolic/oxidative	1.040 ± 0.47	0.999 ± 0.23
UCP-1	Metabolic/oxidative	1.173 ± 0.10	0.886 ± 0.27
Brown adipose tissue
IL-6	Proinflammatory	1.059 ± 0.27	1.054 ± 0.32
TNF-α	Proinflammatory	1.073 ± 0.71	1.028 ± 0.37
CCL2	Proinflammatory	1.049 ± 0.15	1.075 ± 0.33
CCL3	Proinflammatory	1.014 ± 0.29	0.988 ± 0.17
CCL7	Proinflammatory	1.021 ± 0.27	1.053 ± 0.13
CXCL1	Proinflammatory	1.045 ± 0.06	1.023 ± 0.29
Socs3	Proinflammatory	1.045 ± 0.17	1.052 ± 0.32
Socs5	Proinflammatory	1.042 ± 0.34	1.021 ± 0.10
CD68	Macrophage marker	1.056 ± 0.53	0.994 ± 0.15
CD116	Macrophage marker	1.039 ± 0.23	0.971 ± 0.22
CoxIV	Metabolic/oxidative	1.019 ± 0.20	1.000 ± 0.03
PGC-1α	Metabolic/oxidative	0.973 ± 0.18	0.967 ± 0.15
CPT1β	Metabolic/oxidative	0.985 ± 0.29	0.988 ± 0.07
PPAR-α	Metabolic/oxidative	0.986 ± 0.11	1.006 ± 0.04
UCP-1	Metabolic/oxidative	0.985 ± 0.08	0.954 ± 0.24