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. 2013 Dec 3;289(4):2318–2330. doi: 10.1074/jbc.M113.533588

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© 2014 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 3. — Inhibitory effects of G418, NB84, and rotenone (Rot) on mitochondrial respiration in HeLa cells. A, representative tracings of oxygen consumption as recorded by using Clark oxygen electrode. Rates for oxygen consumption in control (Cont, untreated), NB84-, G418-, and rotenone-treated cells were 11.3, 9.6, 6.5, and 4.4 μmole/liter/min, respectively. B, mitochondrial respiration inhibition induced by the indicated concentrations of G418, NB84, and rotenone. Respiration was calculated as a percentage of control. The data represent means ± S.D., n = 3/point.