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HEK293 cells expressing mutant αIIbβ3 receptors support delayed clot retraction
| Cell line | Lag phase | Final clot volume |
|---|---|---|
| min | % | |
| WT αIIbβ3 | 38 ± 3 | 42 ± 6 |
| E157A/D159S/W162F | 50 ± 2 | 43 ± 3 |
| E243L/D247A/E252S | 90 ± 5 | 50 ± 3 |
| D428T/D429M | 42 ± 3 | 46 ± 5 |
| 10-Residue mutant | 110 ± 8 | 70 ± 4 |
