Table 4.
|
Unadjusted |
Adjusted
e
|
||||
---|---|---|---|---|---|---|
IRR (95% CI) | SE d | p-value | IRR (95% CI) | SE d | p-value | |
Indiv_MO12a | ||||||
Group |
1.002 (0.895 – 1.121) |
0.057 |
0.98 |
1.004 (0.903 – 1.116) |
0.054 |
0.94 |
Time |
1.014 (1.001 – 1.023) |
0.005 |
0.002 |
1.017 (1.008 – 1.026) |
0.005 |
<0.001 |
Time2 |
1.002 (1.001 – 1.003) |
0.0003 |
<0.001 |
1.002 (1.001 – 1.003) |
0.0003 |
<0.001 |
Group × Time |
1.001 (0.995 – 1.008) |
0.003 |
0.73 |
1.002 (0.995 – 1.009) |
0.003 |
0.56 |
Indiv_MO6b | ||||||
Group |
1.011 (0.913 – 1.120) |
0.053 |
0.84 |
1.008 (0.923 – 1.101) |
0.045 |
0.86 |
Time |
1.038 (1.030 – 1.046) |
0.004 |
<0.001 |
1.044 (1.036 – 1.052) |
0.004 |
<0.001 |
Group × Time |
0.990 (0.980 – 1.001) |
0.005 |
0.066 |
0.989 (0.978 – 0.9997) |
0.005 |
0.044 |
Indiv_MO3c | ||||||
Group |
0.990 (0.895 – 1.094) |
0.051 |
0.84 |
1.013 (0.926 – 1.108) |
0.046 |
0.77 |
Time |
1.036 (1.024 – 1.050) |
0.007 |
<0.001 |
1.046 (1.031 – 1.062) |
0.008 |
<0.001 |
Group × Time | 0.998 (0.980 – 1.017) | 0.009 | 0.86 | 0.996 (0.975 – 1.018) | 0.011 | 0.74 |
aIndiv_MO12 for the study patients with 12 months’ individual follow-up using exchangeable working correlation structure.
bIndiv_MO6 for the study patients with six months’ individual follow-up using exchangeable working correlation structure.
cIndiv_MO3 for the study patients with three months’ individual follow-up using the auto-regressive (AR1) working correlation structure.
dSemi-Robust Huber/White sandwich estimated standard errors.
eAdjusted for age, gender, number of diagnoses and number of medications.