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. 2013 Dec 23;9:261. doi: 10.1186/1746-6148-9-261

Table 4.

Mean total multi-dose propofol (MDP) required for induction of anesthesia, grouped by premedicant 1

Premedicant None Midazolam Acepromazine Medetomidine
Number of animals
23
47
45
20
Total MDP dose (mg/kg) 2
7.55
4.70
4.00
3.15
Standard deviation
2.14
1.34
0.95
1.38
Range 4.6-16.0 2.2-8.3 1.8-5.1 1.7-7.5

1Sedative and tranquilizers given in combination with buprenorphine; use of anticholinergics was optional. See text for additional detail.

2Statistically significant (p < 0.05) differences: None > (Midazolam, Acepromazine and Medetomidine) and Midazolam > Medetomidine.