Table 2.
drug and prodrugs |
IC50 (95% CI) | Hill slope (95% CI) | R 2 |
---|---|---|---|
CPT | 5.379 (4.409/6.562) | −0.692(−0768/−0.617) | 0.9796 |
2a | 12.24 (10.04/14.93) | −0.622 (−690/−0.555) | 0.9769 |
2b | 120.1 (94.15/153.3) | −0.565 (−0.634/−0.495) | 0.9594 |
2c | 4.103 (3.226/5.218) | −0.649 (−0.739/−0.560) | 0.9662 |
2d | 5.203 (4.141/6.537) | −0.443 (−0.483/−0.403) | 0.9734 |
IC50 is expressed in units of nM