Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Best-Fit Parameters of Cytotoxic Activity of CPT and 2a–d to the Human Lung Carcinoma A549 Cellsa
| drug and prodrugs |
IC50 (95% CI) | Hill slope (95% CI) | R 2 |
|---|---|---|---|
| CPT | 5.379 (4.409/6.562) | −0.692(−0768/−0.617) | 0.9796 |
| 2a | 12.24 (10.04/14.93) | −0.622 (−690/−0.555) | 0.9769 |
| 2b | 120.1 (94.15/153.3) | −0.565 (−0.634/−0.495) | 0.9594 |
| 2c | 4.103 (3.226/5.218) | −0.649 (−0.739/−0.560) | 0.9662 |
| 2d | 5.203 (4.141/6.537) | −0.443 (−0.483/−0.403) | 0.9734 |
IC50 is expressed in units of nM
