Table 3.

Case definitions of Lymeneuroborreliosis.

Confirmed	Probable
Clinical findings compatible with disease CSF lymphocytic pleocytosis ≥5 MNC /µL Intrathecal production of specific anti-Borrelia IgG antibodies	Clinical findings compatible with disease Adequate response to therapy Detectable seroconversion or increasing titers of specific anti-Borrelia IgG antibodies in serum CSF lymphocytic pleocytosis ≥5 MNC/µL or intrathecal production of specific anti-Borrelia IgG antibodies or significant damage to BBB

CSF = cerebrospinal fluid; BBB = blood-brain-barrier; MNC = mononuclear leucocytes; IgG = immunoglobulin G.