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. 2012 Oct 19;1(4):886–904. doi: 10.3390/cells1040886

Figure 1.

Figure 1

Expression of Hippo pathway components and Ste20-like kinases in HepG2 and MCF7 cell lines. (A) Transcript expression levels of Hippo pathway components (left) and Ste20-like kinases (right) do not change in response to rapamycin treatment in HepG2 cells. Mob1, TAO2, Map4K5 and Scrib are expressed at very low levels. (B) Expression levels of Hippo pathway components and Ste20-like kinases transcripts do not change in response to rapamycin treatment in MCF7 cells. Pak1, TAO2, Map4K3, Map4K4, Stradα and STK24 are expressed at low levels. YAP1 is not expressed. Note: Mob1, Map4K5, STK25 and Scrib are expressed at higher levels in MCF7 cells than in HepG2 cells, while Map4K4 and Stradα are expressed at lower levels in MCF7 cells than in HepG2 cells. For both cell lines, GAPDH and the ribosomal protein rpS6 are included as housekeeping gene controls.