Figure 1.
Pathways of arachidonic acid metabolism. Abbreviations: COX, cyclooxygenase; CYP, cytochrome P540; EET, epoxyeicosatrienoic acid; EH, epoxide hydrolase; FLAP, 5-lipoxygenase activating protein; GGT, γ-glutamyltranspeptidase; GSH, glutathione; GST, glutathione-S-transferase; H, hydrolase; HEDH, hydroxyeicosanoid dehydrogenase; HETE, hydroxyeicosatetraenoic acid; HPETE, hydroperoxyeicosatetraenoic acid; HX, hepoxillin; LOX, lipoxygenase; LT, leukotriene; LX, lipoxins; PG, prostaglandin; PGDH, prostaglandin dehydrogenase; POX, peroxidase; S, synthase; TX thromboxane; UGT, UDP-glucuronosyltransferases.