Table 1.

Exoglycosidases and exosulphatases for HS structural analysis. Sulphatases remove sulphate groups from the non-reducing end (NRE) and glycosidases cleave the whole non-sulphated monosaccharides. Information as taken from [38].

Enzyme	Substrate Specificity
Bacterial Exoenzyme
Δ4,5-glycuronate-2-sulphatase	ΔUA(2S)
Δ4,5-glycuronidase	ΔUA
Exoglycosidases
Iduronidase	IdoA
Glucuronidase	GlcA
α- N-acetylglucaminidase	GlcNAc
Exosulphatases
Iduronate-2-sulphatase	IdoA(2S)
Glucosamine-6-sulphatase	GlcNAc(6S). GlcNS (6S)
Sulphaminidase (glucosamine N –sulphatase)	GlcNS
Glucuronate -2-sulphatase	GlcA(2S)
Glucosamine -3-sulphatase	GlcNS(3S)