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. 2013 Apr 18;3(2):294–311. doi: 10.3390/metabo3020294

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© 2013 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Pathways of lysine, methionine and threonine synthesis. Reactions denoted as numbers are catalyzed by following enzymes: (1) aspartate kinase, (2) aspartate semialdehyde dehydrogenase, (3) homoserine dehydrogenase, (4) homoserine kinase, (5) cystathionine-γ-synthase,(6) cystathionine-β-lyase, (7) methionine synthase, (8) threonine synthase, (9) dihydrodipicolinate synthase, (10) dihydrodipicolinate reductase, (11) LL-diaminopimelate aminotransferase, (12) diaminopimelate epimerase, (13) diaminopimelate epimerase, (14) asparagine synthetase, (15) ammonia:aspartate ligase.